RPE Adenocarcinoma as the Presenting Sign of Bronchogenic Carcinoma: Diagnostic Dilemma in the Management of a Case
Histopathological photomicrograph (H & E stain) showing (a) low magnification (4x) intraocular tumor at posterior pole of the globe arising from the RPE sitting over the optic nerve head (dotted arrow) and infiltrating into the choroid. (a) High magnification (40x) typical papillary pattern with round to oval cells with vesicular nuclei suggestive of adenocarcinoma. Focal areas showing pigmentation are seen. (c) Tumor seen breaking through the RPE (arrow) and infiltrating the choroid. (d) Tumor arising from the RPE and involving the optic nerve (dashed arrow).