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Case Reports in Ophthalmological Medicine
Volume 2015, Article ID 179609, 3 pages
Case Report

Benign Lymphoid Hyperplasia Presenting as Bilateral Scleral Nodules

Ophthalmology Department, Pediatric Service, University of Puerto Rico, Medical Science Campus, P.O. Box 365067, San Juan, PR 00936, USA

Received 16 April 2015; Accepted 22 July 2015

Academic Editor: Frederic Mouriaux

Copyright © 2015 Ricardo J. Cumba and Rene Vazquez-Botet. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To report a case of transient lymphoid hyperplasia presenting as bilateral nodular scleral mass in a young male patient. Design. Observational case report. Methods. Chart review. Causes of scleritis were considered and excluded based on detailed history, physical examination, and laboratory investigations. Results. Excisional biopsy of scleral lesions indicated lymphoid tissue. Immunohistochemical studies revealed a polyclonal population of T and B cells consistent with a benign reactive process. Conclusions. Chronic exposure of the ocular adnexa to many allergens and irritants may lead to activation of the inflammatory cascade. In severely allergic patients activation may be exponential and elicit an immune-mediated response resulting in a transient lymphoid reactive process.