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Case Reports in Ophthalmological Medicine
Volume 2015, Article ID 613273, 6 pages
http://dx.doi.org/10.1155/2015/613273
Case Report

Methicillin-Resistant Staphylococcus aureus Ocular Infection after Corneal Cross-Linking for Keratoconus: Potential Association with Atopic Dermatitis

Department of Head and Neck Surgery, Ophthalmology Unit, Catholic University of the Sacred Heart “A. Gemelli”, Largo “A. Gemelli” 8, 00168 Rome, Italy

Received 28 November 2014; Revised 11 March 2015; Accepted 11 March 2015

Academic Editor: Vishal Jhanji

Copyright © 2015 Romina Fasciani et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Y. S. Rabinowitz, “Keratoconus,” Survey of Ophthalmology, vol. 42, no. 4, pp. 297–319, 1998. View at Publisher · View at Google Scholar · View at Scopus
  2. G. Wollensak, E. Spoerl, and T. Seiler, “Riboflavin/ultraviolet-A-induced collagen crosslinking for the treatment of keratoconus,” American Journal of Ophthalmology, vol. 135, no. 5, pp. 620–627, 2003. View at Publisher · View at Google Scholar · View at Scopus
  3. F. Raiskup-Wolf, A. Hoyer, E. Spoerl, and L. E. Pillunat, “Collagen crosslinking with riboflavin and ultraviolet-A light in keratoconus: long-term results,” Journal of Cataract & Refractive Surgery, vol. 34, no. 5, pp. 796–801, 2008. View at Publisher · View at Google Scholar · View at Scopus
  4. A. Caporossi, C. Mazzotta, S. Baiocchi, and T. Caporossi, “Long-term results of riboflavin ultraviolet a corneal collagen cross-linking for keratoconus in Italy: the siena eye cross study,” American Journal of Ophthalmology, vol. 149, no. 4, pp. 585–593, 2010. View at Publisher · View at Google Scholar · View at Scopus
  5. F. Raiskup, A. Hoyer, and E. Spoerl, “Permanent corneal haze after riboflavin-UVA-induced cross-linking in keratoconus,” Journal of Refractive Surgery, vol. 25, no. 9, pp. S824–S828, 2009. View at Publisher · View at Google Scholar · View at Scopus
  6. C. Mazzotta, A. Balestrazzi, S. Baiocchi, C. Traversi, and A. Caporossi, “Stromal haze after combined riboflavin-UVA corneal collagen cross-linking in keratoconus: in vivo confocal microscopic evaluation,” Clinical & Experimental Ophthalmology, vol. 35, no. 6, pp. 580–582, 2007. View at Publisher · View at Google Scholar · View at Scopus
  7. T. Koller, M. Mrochen, and T. Seiler, “Complication and failure rates after corneal crosslinking,” Journal of Cataract and Refractive Surgery, vol. 35, no. 8, pp. 1358–1362, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. R. I. Angunawela, F. Arnalich-Montiel, and B. D. S. Allan, “Peripheral sterile corneal infiltrates and melting after collagen crosslinking for keratoconus,” Journal of Cataract and Refractive Surgery, vol. 35, no. 3, pp. 606–607, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. M. Pollhammer and C. Cursiefen, “Bacterial keratitis early after corneal crosslinking with riboflavin and ultraviolet-A,” Journal of Cataract and Refractive Surgery, vol. 35, no. 3, pp. 588–589, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. P. Rama, F. Di Matteo, S. Matuska, G. Paganoni, and A. Spinelli, “Acanthamoeba keratitis with perforation after corneal crosslinking and bandage contact lens use,” Journal of Cataract & Refractive Surgery, vol. 35, no. 4, pp. 788–791, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. G. D. Kymionis, D. M. Portaliou, D. I. Bouzoukis et al., “Herpetic keratitis with iritis after corneal crosslinking with riboflavin and ultraviolet A for keratoconus,” Journal of Cataract and Refractive Surgery, vol. 33, no. 11, pp. 1982–1984, 2007. View at Publisher · View at Google Scholar · View at Scopus
  12. G. D. Kymionis, D. I. Bouzoukis, V. F. Diakonis, D. M. Portaliou, A. I. Pallikaris, and S. H. Yoo, “Diffuse lamellar keratitis after corneal crosslinking in a patient with post-laser in situ keratomileusis corneal ectasia,” Journal of Cataract and Refractive Surgery, vol. 33, no. 12, pp. 2135–2137, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. N. Sharma, P. Maharana, G. Singh, and J. S. Titiyal, “Pseudomonas keratitis after collagen crosslinking for keratoconus: case report and review of literature,” Journal of Cataract and Refractive Surgery, vol. 36, no. 3, pp. 517–520, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. M. Bödemann and T. Kohnen, “Corneal ulcer caused by MRSA after UV/riboflavin cross-linking in a patient with bilateral keratoconus,” Ophthalmologe, vol. 109, no. 11, pp. 1112–1114, 2012. View at Publisher · View at Google Scholar · View at Scopus
  15. G. Ferrari, L. Iuliano, M. Viganò, and P. Rama, “Impending corneal perforation after collagen cross-linking for herpetic keratitis,” Journal of Cataract and Refractive Surgery, vol. 39, no. 4, pp. 638–641, 2013. View at Publisher · View at Google Scholar · View at Scopus
  16. M. Rana, A. Lau, A. Aralikatti, and S. Shah, “Severe microbial keratitis and associated perforation after corneal crosslinking for keratoconus,” Contact Lens and Anterior Eye, vol. 38, no. 2, pp. 134–137, 2015. View at Publisher · View at Google Scholar
  17. J. Sugar and M. S. MacSai, “What causes keratoconus?” Cornea, vol. 31, no. 6, pp. 716–719, 2012. View at Publisher · View at Google Scholar · View at Scopus
  18. I. Rystedt, I.-L. Strannegard, and O. Strannegard, “Infections of contributing factors to atopic dermatitis,” Allergy, vol. 44, no. 9, pp. 79–83, 1989. View at Google Scholar · View at Scopus
  19. Y. Inoue, “Ocular infections in patients with atopic dermatitis,” International Ophthalmology Clinics, vol. 42, no. 1, pp. 55–69, 2002. View at Google Scholar · View at Scopus
  20. A. M. Schimel, D. Miller, and H. W. Flynn Jr., “Endophthalmitis isolates and antibiotic susceptibilities: a 10-year review of culture-proven cases,” American Journal of Ophthalmology, vol. 156, no. 1, pp. 50.e1–52.e1, 2013. View at Publisher · View at Google Scholar · View at Scopus
  21. M. L. Durand, “Endophthalmitis,” Clinical Microbiology and Infection, vol. 19, no. 3, pp. 227–234, 2013. View at Publisher · View at Google Scholar · View at Scopus
  22. C. Sotozono, M. Fukuda, M. Ohishi et al., “Vancomycin Ophthalmic Ointment 1% for methicillin-resistant Staphylococcus aureus or methicillinresistant Staphylococcus epidermidis infections: a case series,” BMJ Open, vol. 3, no. 1, Article ID e001206, 2013. View at Publisher · View at Google Scholar · View at Scopus
  23. L. Spadea and A. Fiasca, “Treatment of post-operative endophthalmitis,” European Ophthalmic Review, vol. 6, no. 3, pp. 149–156, 2012. View at Google Scholar
  24. P. Rama, F. di Matteo, S. Matuska, G. Paganoni, and A. Spinelli, “Acanthamoeba keratitis with perforation after corneal crosslinking and bandage contact lens use,” Journal of Cataract and Refractive Surgery, vol. 35, no. 4, pp. 788–791, 2009. View at Publisher · View at Google Scholar · View at Scopus
  25. N. Sharma, P. Maharana, G. Singh, and J. S. Titiyal, “Pseudomonas keratitis after collagen crosslinking for keratoconus: case report and review of literature,” Journal of Cataract and Refractive Surgery, vol. 36, no. 3, pp. 517–520, 2010. View at Publisher · View at Google Scholar · View at Scopus
  26. A. Pantosti and M. Venditti, “What is MRSA?” European Respiratory Journal, vol. 34, no. 5, pp. 1190–1196, 2009. View at Publisher · View at Google Scholar · View at Scopus
  27. E. S. Yang, J. Tan, S. Eells, G. Rieg, G. Tagudar, and L. G. Miller, “Body site colonization in patients with community-associated methicillin-resistant Staphylococcus aureus and other types of S. Aureus skin infections,” Clinical Microbiology and Infection, vol. 16, no. 5, pp. 425–431, 2010. View at Publisher · View at Google Scholar · View at Scopus
  28. K. Nakata, Y. Inoue, J. Harada et al., “A high incidence of Staphylococcus aureus colonization in the external eyes of patients with atopic dermatitis,” Ophthalmology, vol. 107, no. 12, pp. 2167–2171, 2000. View at Publisher · View at Google Scholar · View at Scopus
  29. Y. Oshima, M. Ohji, Y. Inoue et al., “Methicillin-resistant Staphylococcus aureus infections after scleral buckling procedures for retinal detachments associated with atopic dermatitis,” Ophthalmology, vol. 106, no. 1, pp. 142–147, 1999. View at Publisher · View at Google Scholar · View at Scopus
  30. R. Shetty, L. Kaweri, R. M. M. A. Nuijts, H. Nagaraja, V. Arora, and R. S. Kumar, “Profile of microbial keratitis after corneal collagen cross-linking,” BioMed Research International, vol. 2014, Article ID 340509, 7 pages, 2014. View at Publisher · View at Google Scholar
  31. A. Toshitani, S. Imayama, Y. Shimozono, T. Yoshinaga, M. Furue, and Y. Hori, “Reduced amount of secretory component of IgA secretion in tears of patients with atopic dermatitis,” Journal of Dermatological Science, vol. 19, no. 2, pp. 134–138, 1999. View at Publisher · View at Google Scholar · View at Scopus
  32. K. Jujo, H. Renz, J. Abe, E. W. Gelfand, and D. Y. M. Leung, “Decreased interferon gamma and increased interleukin-4 production in atopic dermatitis promotes IgE synthesis,” Journal of Allergy and Clinical Immunology, vol. 90, no. 3, pp. 323–331, 1992. View at Publisher · View at Google Scholar · View at Scopus
  33. K. Nakata, Y. Inoue, J. Harada et al., “A high incidence of Staphylococcus aureus colonization in the external eyes of patients with atopic dermatitis,” Ophthalmology, vol. 107, no. 12, pp. 2167–2171, 2000. View at Publisher · View at Google Scholar · View at Scopus
  34. A. Rahi, P. Davies, M. Ruben, D. Lobascher, and J. Menon, “Keratoconus and coexisting atopic disease,” British Journal of Ophthalmology, vol. 61, no. 12, pp. 761–764, 1977. View at Publisher · View at Google Scholar · View at Scopus
  35. P. W. Copeman, “Eczema and keratoconus,” British Medical Journal, vol. 2, no. 5468, pp. 977–979, 1965. View at Publisher · View at Google Scholar · View at Scopus
  36. R. J. Harrison, P. T. Klouda, D. L. Easty, M. Manku, J. Charles, and J. C. C. M. Stewart, “Association between keratoconus and atopy,” British Journal of Ophthalmology, vol. 73, no. 10, pp. 816–822, 1989. View at Publisher · View at Google Scholar · View at Scopus
  37. L. Wachtmeister, S. O. Ingemansson, and E. Moller, “Atopy and HLA antigens in patients with keratoconus,” Acta Ophthalmologica, vol. 60, no. 1, pp. 113–122, 1982. View at Google Scholar · View at Scopus
  38. K. H. Weed, C. J. MacEwen, T. Giles, J. Low, and C. N. J. McGhee, “The Dundee University Scottish Keratoconus study: demographics, corneal signs, associated diseases, and eye rubbing,” Eye, vol. 22, no. 4, pp. 534–541, 2008. View at Publisher · View at Google Scholar · View at Scopus
  39. R. Solomon, E. D. Donnenfeld, E. J. Holland et al., “Microbial keratitis trends following refractive surgery: results of the ASCRS infectious keratitis survey and comparisons with prior ASCRS surveys of infectious keratitis following keratorefractive procedures,” Journal of cataract and refractive surgery, vol. 37, no. 7, pp. 1343–1350, 2011. View at Publisher · View at Google Scholar · View at Scopus
  40. G. Labiris, A. Giarmoukakis, R. Larin, H. Sideroudi, and V. P. Kozobolis, “Corneal collagen cross-linking in a late-onset graft infectious ulcer: a case report,” Journal of Medical Case Reports, vol. 8, article 180, 2014. View at Publisher · View at Google Scholar · View at Scopus
  41. J. L. Alio, A. Abbouda, D. D. Valle, J. M. B. del Castillo, and J. A. G. Fernandez, “Corneal cross linking and infectious keratitis: a systematic review with a meta-analysis of reported cases,” Journal of Ophthalmic Inflammation and Infection, vol. 3, no. 1, article 47, 2013. View at Google Scholar
  42. E. Y. Tu and S. Jain, “Topical linezolid 0.2% for the treatment of vancomycin-resistant or vancomycin-intolerant gram-positive bacterial keratitis,” The American Journal of Ophthalmology, vol. 155, no. 6, pp. 1095.e1–1098.e1, 2013. View at Publisher · View at Google Scholar · View at Scopus
  43. D. M. Buzzacco and C. P. Carroll, “Intravitreal daptomycin in a case of bilateral endogenous endophthalmitis,” Archives of Ophthalmology, vol. 130, no. 7, pp. 940–941, 2012. View at Publisher · View at Google Scholar · View at Scopus
  44. T. Agarwal, V. Jhanji, G. Satpathy et al., “Moxifloxacin resistance: intrinsic to antibiotic or related to mutation?” Optometry & Vision Science, vol. 89, no. 12, pp. 1721–1724, 2012. View at Publisher · View at Google Scholar · View at Scopus
  45. C. E. Haley, M. Marling-Cason, J. W. Smith, J. P. Luby, and P. A. Mackowiak, “Bactericidal activity of antiseptics against methicillin-resistant Staphylococcus aureus,” Journal of Clinical Microbiology, vol. 21, no. 6, pp. 991–992, 1985. View at Google Scholar · View at Scopus
  46. B. Li, M. M. Nentwich, L. E. Hoffmann et al., “Comparison of the efficacy of povidone-iodine 1.0%, 5.0%, and 10.0% irrigation combined with topical levofloxacin 0.3% as preoperative prophylaxis in cataract surgery,” Journal of Cataract & Refractive Surgery, vol. 39, no. 7, pp. 994–1001, 2013. View at Publisher · View at Google Scholar · View at Scopus
  47. H. Hosseini, M. J. Ashraf, M. Saleh et al., “Effect of povidone-iodine concentration and exposure time on bacteria isolated from endophthalmitis cases,” Journal of Cataract and Refractive Surgery, vol. 38, no. 1, pp. 92–96, 2012. View at Publisher · View at Google Scholar · View at Scopus
  48. M. M. Nentwich, M. Rajab, C. N. Ta et al., “Application of 10% povidone iodine reduces conjunctival bacterial contamination rate in patients undergoing cataract surgery,” European Journal of Ophthalmology, vol. 22, no. 4, pp. 541–546, 2012. View at Publisher · View at Google Scholar · View at Scopus
  49. S. J. Isenberg, L. Apt, M. Valenton et al., “A controlled trial of povidone-iodine to treat infectious conjunctivitis in children,” The American Journal of Ophthalmology, vol. 134, no. 5, pp. 681–688, 2002. View at Publisher · View at Google Scholar · View at Scopus
  50. T. Yoshida and K. Hiramatsu, “Potent in vitro bactericidal activity of polymyxin B against methicillin- resistant Staphylococcus aureus (MRSA),” Microbiology and Immunology, vol. 37, no. 11, pp. 853–859, 1993. View at Publisher · View at Google Scholar · View at Scopus