Brittle Cornea Syndrome: Case Report with Novel Mutation in the PRDM5 Gene and Review of the Literature

Figure 1

Acute keratoconus with hydrops in a 3-year-old child with brittle cornea syndrome. (A) Left eye three months after acute keratoconus with already clearing corneal cloudiness. (B) Seven months after acute keratoconus only little subepithelial scars remained. (C) Optical coherence tomography (OCT) at 7 months after acute hydrops demonstrated steepness and thinning of cornea. Corneal thickness centrally was 259 μm.