Case Report

Pseudotumor Cerebri in a Child with Idiopathic Growth Hormone Insufficiency Two Months after Initiation of Recombinant Human Growth Hormone Treatment

Box 2

Diagnostic criteria for prepubertal PTC.
(1) Symptoms or signs of generalized intracranial hypertension or papilledema with normal mental status
(2) Documented elevated intracranial pressure (age appropriate) measured in the lateral decubitus position;
neonates: >76 mm H2O, age 1–18 years: >280 mm H2O
(3) Normal CSF composition except in neonates who may have up to 19 WBC/mm3 if 0–28 days and
up to 9 WBC/mm3 if between 29 and 56 days of age; the protein may be as high as 150 mg/dL
(4) No evidence of hydrocephalus, mass, structural, or vascular lesion on MRI,
with and without contrast, and MR venography; narrowing of the transverse sinuses is allowed
(5) Cranial nerve palsies without any other identifiable etiology which improve with reduction of
cerebrospinal fluid pressure or resolution of other signs and symptoms of intracranial hypertension
(6) No other identified cause of intracranial hypertension