Case Report
Pseudotumor Cerebri in a Child with Idiopathic Growth Hormone Insufficiency Two Months after Initiation of Recombinant Human Growth Hormone Treatment
Box 2
Diagnostic criteria for prepubertal PTC.
(1) Symptoms or signs of generalized intracranial hypertension or papilledema with normal mental status | (2) Documented elevated intracranial pressure (age appropriate) measured in the lateral decubitus position; | neonates: >76 mm H2O, age 1–18 years: >280 mm H2O | (3) Normal CSF composition except in neonates who may have up to 19 WBC/mm3 if 0–28 days and | up to 9 WBC/mm3 if between 29 and 56 days of age; the protein may be as high as 150 mg/dL | (4) No evidence of hydrocephalus, mass, structural, or vascular lesion on MRI, | with and without contrast, and MR venography; narrowing of the transverse sinuses is allowed | (5) Cranial nerve palsies without any other identifiable etiology which improve with reduction of | cerebrospinal fluid pressure or resolution of other signs and symptoms of intracranial hypertension | (6) No other identified cause of intracranial hypertension |
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