Presumed Retinal Metastasis from Lung Adenocarcinoma: A Case Report and Literature Review

Figure 1

(a) Whitish perivascular retinal lesion measuring approximately 0.5 x 0.5 x 0.5 mm located along the inferotemporal arcade in the right eye. (b) The lesion is hyporeflective on infrared imaging. (c) The lesion shows hypoautofluorescence on fundus autofluorescence imaging. (d) Spectral domain optical coherence tomography (SD-OCT) imaging shows the hyperreflective dome-shaped lesion replacing inner retinal structures, causing disorganization and compression of the outer retina. Multiple hyperreflective dots are observed overlying the retina consistent with tumor cells in the posterior vitreous (arrowhead). Ellipsoid zone cannot be observed clearly because of partial posterior shadowing by the tumor, but the retinal pigment epithelium is intact. (e) At 2 months follow-up examination after completion of chemotherapy, the retinal lesion regressed completely leaving only focal irregularities in the inner retinal layers on SD-OCT.

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