Multicentric Giant Cell Tumor of Bone: Synchronous and Metachronous Presentation

Figure 7

Microscopic pathology: H-E stain at 200x at the lesion of the right femur: the specimen demonstrated large osteoclasts and uniform mononuclear cells with ovoid nuclei, giant cells containing about 50 to 100 nuclei, and ill-defined cytoplasm with very few intercellular collagen.