Case Report

Inflammatory Myofibroblastic Tumor of the Thigh: Presentation of a Rare Case and Review of the Literature

Table 1

Clinical and pathological features helping differential diagnosis of inflammatory myofibroblasic tumor.

Features that favor IMTFeatures that argue against IMT

Child or young adultMiddle aged or older adult
Mass in lung or soft tissue of abdomen, pelvis, and retroperitoneumMass of the skin or subcutis, lymph nodes, spleen, or bladder
Diffuse inflammatory infiltrate, prominent plasma cellsPatchy inflammatory infiltrate. Predominantly lymphocytic
Mild nuclear atypia, scattered ganglion-like cellsModerate to severe nuclear atypia with hyperchromasia
Low mitotic rate, no atypical formsAtypical mitoses
ALK positivity by immunohistochemistry or ALK gene rearrangementNecrosis