Potential Complications of Percutaneous Vertebroplasty Combined with Interstitial Implantation of ¹²⁵I Seeds for Metastatic Spinal Tumors: A Case Report and Literary Review

Table 1

The published literatures of novel therapeutic methods for spinal metastatic tumors.

Year and author	Size of sample		Age (years)	Follow-up time (months)	Dosage (seeds per patient)	Tools of evaluation	Complications	Therapeutic effects
	Male	Female
								Clinical states	Radiological manifestations
2009, Yang et al. [5]	21	19		12	2.92; 5–10	VAS, KPS, RECIST, CT, MRI	Bone cement leakage	Alleviate back pain; Improve quality of life	Acquire spinal stability; Prohibit and kill tumor cells
2011, Zuozhang et al. [9]	1	—	38	36	2.92	VAS, KPS, RECIST, CT, MRI	No complications
2012, Yang et al. [10]	20	30		12	7–20; 80–100^#	VAS, QLQ-C30, CT, MRI	Low blood pressure; Low oxygen saturation; High level of thromboses
2014, Li et al. [6]	18	11	49.2	3	90–140^#	VAS, KPS, RECIST, CT, MRI	Bone cement leakage
2014, Huang et al. [11]	10	8	62	6	16-34	VAS, KPS, ECT, CT	Bone cement leakage

cGy/hour/seed; ^#Gy.