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Case Reports in Otolaryngology
Volume 2013, Article ID 578606, 4 pages
Case Report

Laryngeal Synovial Sarcoma: A Rare Clinical Entity

1St Vincents Hospital, Sydney, NSW 2010, Australia
2St Vincents Clinic, Sydney, NSW 2010, Australia

Received 12 May 2013; Accepted 16 June 2013

Academic Editors: E. Mevio, K. Morshed, Y. Orita, and M. S. Timms

Copyright © 2013 Clair Saxby et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Introduction. Synovial sarcomas (SS) are aggressive malignant soft tissue tumours that are thought to arise from pluripotent mesenchymal cells. Clinical Report. A 20-year-old male presented with an acute onset of respiratory stridor. Computer tomography scanning confirmed a mass arising from the left supraglottic larynx and an emergency tracheostomy was performed. A diagnosis of biphasic synovial sarcoma was formed. A total laryngectomy and left hemithyroidectomy was performed in conjunction with a left modified radical neck dissection. The patient received adjuvant chemotherapy followed by a course of radiotherapy and remains alive and disease free at 18 months after treatment. Discussion. Prognosis for patients with SS is related to primary tumour extent, grade, and size. The presence of the diagnostic translocation, t(X;18), is being targeted and hopefully will lead to the development of new therapeutics (Guadagnolo et al., 2007). Conclusion. Laryngeal SS remains a rare and poorly understood entity. A multidisciplinary approach to treatment is essential and long-term followup is imperative.