TY - JOUR A2 - Yokoi, H. A2 - Balatsouras, D. G. A2 - Timms, M. S. AU - Sahai, Puja AU - Mohanti, Bidhu Kalyan AU - Nath, Devajit AU - Bhasker, Suman AU - Chander, Subhash AU - Bakhshi, Sameer AU - Singh, Chirom Amit PY - 2014 DA - 2014/03/18 TI - Malignant Peripheral Nerve Sheath Tumour of the Maxilla SP - 230849 VL - 2014 AB - A 38-year-old man was diagnosed with malignant peripheral nerve sheath tumour of the maxilla. He was treated with total maxillectomy. Histopathological examination of the resected specimen revealed a close resection margin. The tumour was of high grade with an MIB-1 labelling index of almost 60%. At six weeks following the surgery, he developed local tumour relapse. The patient succumbed to the disease at five months from the time of diagnosis. The present report underlines the locally aggressive nature of malignant peripheral nerve sheath tumour of the maxilla which necessitates an early therapeutic intervention. A complete resection with clear margins is the most important prognostic factor for malignant peripheral nerve sheath tumour in the head and neck region. Adjuvant radiotherapy may be considered to improve the local control. Future research may demarcate the role of targeted therapy for patients with malignant peripheral nerve sheath tumour. SN - 2090-6765 UR - https://doi.org/10.1155/2014/230849 DO - 10.1155/2014/230849 JF - Case Reports in Otolaryngology PB - Hindawi Publishing Corporation KW - ER -