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Case Reports in Otolaryngology
Volume 2015 (2015), Article ID 683938, 3 pages
Case Report

A Three-Generation Family with Idiopathic Facial Palsy Suggesting an Autosomal Dominant Inheritance with High Penetrance

1Department of Otorhinolaryngology, Head and Neck Surgery, Copenhagen University Hospital of Rigshospitalet, 2100 Copenhagen, Denmark
2Department of Dermato-Allergology, Gentofte Hospital, University of Copenhagen, 2900 Hellerup, Denmark
3Clinical Genetic Clinic, Kennedy Center, Copenhagen University Hospital, Rigshospitalet, 2600 Glostrup, Denmark
4Applied Human Molecular Genetics, Kennedy Center, Copenhagen University Hospital, Rigshospitalet, 2600 Glostrup, Denmark

Received 17 November 2014; Accepted 29 December 2014

Academic Editor: Akinobu Kakigi

Copyright © 2015 Christian Grønhøj Larsen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Idiopathic facial palsy (IFP), also known as Bell’s palsy, is a common neurologic disorder, but recurrent and familial forms are rare. This case series presents a three-generation family with idiopathic facial palsy. The mode of inheritance of IFP has previously been suggested as autosomal dominant with low or variable penetrance, but the present family indicates an autosomal dominant trait with high or complete penetrance. Chromosome microarray studies did not reveal a pathogenic copy number variation, which could enable identification of a candidate gene.