Case Report

High-Grade Transformation (Dedifferentiation) of Acinic Cell Carcinoma of the Parotid Gland: Report of an Unusual Variant

Figure 1

(a) Hematoxylin and eosin stain illustrating a low-grade acinic cell carcinoma at the bottom juxtaposed to a high-grade carcinoma, simulating a salivary duct carcinoma with central necrosis. (b) An area of high-grade transformation demonstrating an infiltrating tumor with extensive central necrosis.
(a)
(b)