Ectopic Functioning Adrenocortical Oncocytic Adenoma (Oncocytoma) with Myelolipoma Causing Virilization
Figure 2
Gross examination of the retroperitoneal mass showed a red-tan smooth-surfaced lobulated mass with areas of fat (a). Microscopic examination showed oncocytes, adipocytes, and trilineage hematopoeisis intimately associated ((b), H&E, 100x). The oncocytes had abundant granular cytoplasm with lipofuscin. Random nuclear atypia is readily apparent but no mitotic activity was identified ((c), H&E, 200x). The oncocytes were interspersed with maturing erythroids and myeloid elements and megakaryocytes ((d), H&E, 200x).