Primary Hairy Cell Leukemia/Lymphoma of the Breast: A Case Report and Review of the Literature

Figure 1

(a) Morphologic examination reveals interstitial lymphocytic infiltrate of small mature lymphocytes (H&E ×200). (b) The neoplastic cells have round nuclear contours, condensed chromatin, inconspicuous nucleoli, and ample pale cytoplasm (H&E ×400). Immunohistochemical staining reveals that the neoplastic cells are CD20 positive B-cells (c) showing cytoplasmic staining for Annexin (d), nuclear staining for Cyclin D1 (e), and cytoplasmic TRAP (f). (Immunoperoxidase ×400).

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