TY - JOUR A2 - Tosi, Piero AU - Modi, Gaurang AU - Madabhavi, Irappa AU - Panchal, Harsha AU - Anand, Asha AU - Patel, Apurva AU - Parikh, Sonia AU - Revannasiddaiah, Swaroop PY - 2014 DA - 2014/12/24 TI - Primary Synovial Sarcoma of Kidney: A Rare Differential Diagnosis of Renomegaly SP - 657497 VL - 2014 AB - Synovial sarcomas (SS) are classified as subgroup of soft tissue sarcomas affecting mainly extremities of young adults. Primary SS of kidney are very rare tumours with poor prognosis. Though they have characteristic histology and immunohistochemistry (IHC) due to rarity of incidence it is difficult to diagnose them. Sometimes chromosomal rearrangement studies are required to confirm the diagnosis. We are presenting a case of 41-year-old male who was referred to our cancer centre for evaluation of left renal mass. CT scan of abdomen revealed a large left renal mass encasing the aorta. Biopsy of renal mass revealed poorly differentiated sarcoma and IHC was positive for vimentin, CD99, and BCL2 and negative for AE1, epithelial membrane antigen, and leukocyte common antigen. The patient was clinically inoperable as renal mass was encasing the aorta. So he was subsequently offered palliative chemotherapy in form of ifosfamide and adriamycin. CT abdomen shows partial response after 3 cycles of chemotherapy according to RECIST criteria. SN - 2090-6781 UR - https://doi.org/10.1155/2014/657497 DO - 10.1155/2014/657497 JF - Case Reports in Pathology PB - Hindawi Publishing Corporation KW - ER -