Case Report

Spontaneous Splenic Rupture in Melanoma

Figure 1

(a) Gross pathology: capsular laceration and hemorrhage and cut sections show diffuse involvement of spleen by creamy homogenous tumoral tissue. (b) Diffuse involvement of spleen by malignant melanoma cells showing fascicular and trabecular pattern (Hematoxylin and Eosin stain, scale bar = 100 μm). Inset shows rhabdoid type tumor cells (Hematoxylin and Eosin stain, scale bar = 50 μm). (c) High power shows tumoral cells in red pulp and sinusoids (Hematoxylin and Eosin stain, scale bar = 25 μm). Inset shows positive immunoperoxidase for HMB-45 in tumoral cells (immunoperoxidase, scale bar = 25 μm).