Case Report

Primary Invasive Squamous Cell Carcinoma of the Nipple

Table 1

Case reports, squamous cell carcinoma of the nipple and areola.

PatientRisk factorsCarcinomaTherapyOutcome

Venkataseshan et al. [4]84 y.o. FNot knownIn situWLEDF × 30 months

Sharma and Iyer [7]41 y.o. MHIV diseaseIn situ
Negative LNs
Mastectomy, SLNDF × 3 years

Brookes et al. [8]71 y.o. FXRTIn situPhotodynamicResidual × 2, cryotherapy
DF × 9 months
69 y.o. FNot knownInvasiveWLERecurrence at 3 months, repeat excision
DF × 6 months

Loveland-Jones et al. [3]66 y.o. FXRTInvasiveWLENot reported

Hosaka et al. [5]73 y.o. FNot knownSuperficially invasive (<1 mm)
Negative LNs
Mastectomy, ALNDDF × 5 years

Upasham et al. [6]87 y.o. FNot knownInvasive
Positive LN 1/11
Mod. rad. mastectomyNot reported

Sofos et al. [1]34 y.o. FNot knownInvasiveWLEDF × 12 months

King and Kremer [2]62 y.o. MSun exposure × 10 yearsInvasive with NE differentiationWLENot reported

XRT = radiation therapy; LN = lymph node; SLN = sentinel lymph node; ALND = axillary lymph node dissection; WLE = wide local excision; DF = disease-free.