Clonal CD8+ T Lymphocytic Proliferation and Karyotypical Abnormalities in an EBV Associated Hemophagocytic Lymphohistiocytosis

Figure 1

Histologic features of bone marrow. (a) Bone marrow biopsy demonstrated hypocellular marrow with prominent lymphohistiocytic infiltrates. Black arrow in the inset pointed to a histiocyte with engulfed hematopoietic elements. (b) Immunohistochemical stain of CD68 showed increased histiocytes. (c) Bone marrow aspirate smears highlighted hemophagocytosis (black arrow) and atypical lymphoid cell (red arrow).

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