MYC Amplification in Angiosarcoma Arising from an Arteriovenous Graft Site

Figure 3

Microscopic examination, amputation specimen. (a) Clusters of malignant epithelioid cells, similar to those seen in the biopsy specimen, are noted (original magnification ×400). (b) Perineural invasion can explain the patient’s pain symptoms (original magnification ×200). (c) Tumor clusters are embedded within the dense fibrous sheath around the graft material; the region marked by the asterisk is shown at higher power in (d) (original magnification ×50, ×400). (e) Tumor cells are seen tracking along the intimal layer of a large artery; the region marked by the asterisk is shown at higher power in (f) (original magnification ×10, ×400).

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