Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Pathology
Volume 2016, Article ID 1871807, 4 pages
Case Report

Hepatoid Adenocarcinoma of the Urachus

1Department of Pathology, University of Washington, Seattle, WA, USA
2Department of Surgery, Mercy Medical Center, Baltimore, MD, USA
3Department of Pathology, Fundacion Valle del Lili, Cali, Colombia
4Department of Pathology, Universidad del Valle, Cali, Colombia

Received 9 July 2016; Accepted 19 September 2016

Academic Editor: Zsuzsa Schaff

Copyright © 2016 Daniel Fernando Gallego et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Hepatoid adenocarcinoma of the urachus is a rare condition. We present the case of a 51-year-old female who developed abdominal pain and hematuria. Pelvic magnetic resonance imaging (MRI) reported an urachal mass with invasion to the bladder that was resected by partial cystectomy. On light microscopy the tumor resembled liver architecture, with polygonal atypical cells in nest formation and trabecular structures. Immunochemistry was positive for alfa-fetoprotein (AFP) and serum AFP was elevated. Hepatoid adenocarcinomas have been reported in multiple organs, being most commonly found in the stomach and the ovaries. Bladder compromise has been rarely described in the literature, and it has been associated with poor prognosis, low remission rates, and early metastasis.