Case Report
Metastatic Gastrointestinal Adenocarcinoma with Osteoblastic Activity: A Case Report of Esophageal and Colonic Primaries
Figure 1
Case histologic features of the esophageal mass and soft tissue mass. (a) Biopsy of the distal esophageal mass demonstrated infiltrating moderately differentiated neoplastic glands consistent with primary esophageal adenocarcinoma in a background of goblet cell (intestinal) metaplasia (H&E, 40x). (b) MRI of the deltoid muscle soft tissue mass highlighted bone and calcifications within the lesion that is distinctly separate from the humerus (red arrow). (c) Resection of the soft tissue mass at low power magnification showed a well-circumscribed mass of neoplastic glands closely associated with osteoblastic activity within skeletal muscle and fibrosis (H&E, 20x). (d) Resection of soft tissue mass at higher magnification highlighted moderately differentiated neoplastic glands with osteoblastic activity, but lacking bone marrow elements (H&E, 100x).
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