Serous Cystadenocarcinoma Arising in Presumed Vitelline Duct Remnant: A Case Report and Implications in the Management of Cancer of Unknown Primary

Figure 5

The tumor demonstrated a spectrum of serous neoplasia, with areas of serous cystadenoma representing the better differentiated component (a, b), papillary serous carcinoma with numerous Psammoma bodies representing the areas of high grade tumor (c, d), and solid sheets of poorly differentiated tumor cells representing the dedifferentiated component (e, f). These morphologic features were those of serous neoplasia with progressive dedifferentiation. Transition zones were present (g, h) (hematoxylin-eosin staining; (a), (c), (e), and (g) 40x; (b) 400x; (d) 600x; (f) 200x; (h) 100x).

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