Case Report

Intrathyroidal Clear Cell Tumor of Parathyroid Origin with Review of Literature

Table 1


LiteratureAge,
sex
DiagnosisFNADimensions in cm; extrathyroidal unless specifiedWeight SymptomsPTH level in pg/mLInitial calcium in mg/dLTreatment

Kovacs et al. 1994 [4]48 MUSNANANANA4310.8Right hemithyroidectomy and total parathyroidectomy
Grenko et al. 1995 [5]40 MNANA5 × 3 × 1.57.6 gFatigue, leg cramps94511.3Parathyroidectomy
Bégueret et al. 1999 [14]73 MNANA2.8 × 1 cmNANephrolithiasis20713.7NA
Dundar et al. 2001 [13]43 F(+) US/(+) sestamibi scanNA6; intrathyroidalNAFractures, cramps, fatigue166713.3Left total and right near total thyroidectomy
Kuhel et al. 2001 [15]56 F(+) US/(−) sestamibi scanFNA colloid noduleRight 2.8
Left 1.5
1.7 g
0.5 g
Asymptomatic5213.2Parathyroidectomy, R thyroid lobectomy, and isthmectomy
Kanda et al. 2004 [2]52 F(+) US/(+) sestamibi scanNA6.8 × 2.8 × 1.915.4 gGastritis, nephrolithiasis67210.7Parathyroidectomy
Prasad et al. 2004 [16]40 F(+) USNA3 × 1.5 × 1.04.2 gFatigue, cramps, weakness34612.4Parathyroidectomy
Kodama et al. 2007 [17]18 F(+) US/(+) sestamibi scanNA5 × 3.3 × 321.7 gRenal stones35611.6Parathyroidectomy
Papanicolau-Sengos et al. 2011 [1]64 M(+) CT chest with contrastFollicular neoplasm of the thyroid4.7 × 3.5 × 1.7NAAsymptomaticNANAParathyroidectomy
Chou et al. 2014 [7]81 F(+) US/(+) sestamibi scanNA3.8NAHyper/pancreatitis45012.0Parathyroidectomy
Bai et al. 2012 [18]81 M(−) US/(+) sestamibi scanNA4 × 2.5 × 1.66.91 gNA211NAParathyroidectomy
Bai et al. 2012 [18]55 M(−) US/(−) sestamibi scanConcomitant papillary thyroid carcinoma1.4 × 0.8 × 0.60.27 gNA151NAThyroidectomy, right neck lymph node dissection, and parathyroidectomy
Piggott et al. 2013 [8]74 F(+) US/(+) sestamibi scanNA5.5 × 2.5 × 213 gAbdominal pain, constipation, lethargy48912.5Parathyroidectomy
Ezzat et al. 2013 [10]73 M(+) US/(+) sestamibi scanNA3.7 × 3.5 × 1.78 gNA29313.0Parathyroidectomy
Ezzat et al. 2013 [10]74 F(+) US/(−) sestamibi scanNA1.6 × 1.2 × 0.30.9 gNA11211.6Parathyroidectomy
Tassone et al. 2014 [9]54 F(+) US/(−) sestamibi scanNA2.8 × 1.1 × 1.1NAHyper/bone pain, depression, forgetfulness13012.4Parathyroidectomy
Murakami et al. 2014 [19]59 F(+) US/(+) CT chest/(−) sestamibi scanNANA; extrathyroidal0.5 gRenal stones, bone fracture7211.9Parathyroidectomy
Current case34 F(+) USThyroid follicular cells without atypia2.5 × 1.7 × 1.5 intrathyroidalNAAsymptomaticNA9.3Thyroidectomy

NA: not available; (+): positive; (−): negative; sestamibi scan: sestamibi scan of the parathyroid; US: US of the thyroid.