Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Pathology
Volume 2017, Article ID 1765460, 6 pages
Case Report

Primary Villoglandular Mucinous Adenocarcinoma of the Vulva

1Division of Pathology, Ryukyu University Hospital, University of the Ryukyus, Okinawa, Japan
2Department of Tumor Pathology, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan

Correspondence should be addressed to Akiko Matsuzaki;

Received 31 October 2016; Revised 3 March 2017; Accepted 4 April 2017; Published 19 April 2017

Academic Editor: Lubos Holubec

Copyright © 2017 Akiko Matsuzaki et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Primary villoglandular mucinous adenocarcinoma of the vulva is rare tumor. We report a case of 68-year-old woman who developed this very uncommon malignant tumor. Immunohistochemical examination of this tumor revealed positive staining for Cytokeratin 20, Mucin 2, and CDX2, although Cytokeratin 7 and Mucin 6 were negative. This positive staining indicated the tumor enteric type characters. In order to exclude the possibility of the metastasis from another site, we thoroughly evaluated clinical data and extensively investigated the whole body. However, we could not detect any other tumors. The patient was treated by tumor resection. The patient remains free of disease 5 years after surgery.