Newly Diagnosed Colonic Adenocarcinoma: The Presenting Sign in a Young Woman with Undiagnosed Crohn’s Disease in the Absence of Primary Sclerosing Cholangitis and a Normal Microsatellite Instability Profile

<div>H&amp;E stained sections demonstrating focal chronic-active colitis, consistent with Crohn’s disease. (a) Low power view showing dense inflammatory infiltrate composed of lymphoid hyperplasia (center and upper left) combined with transmural neutrophilic inflammation forming deep fissuring ulcer (bottom right) (40x), (b-c) crypt distortion, reactive epithelial atypia with neutrophilic inflammation ((b) 100x, (c) 200x), and (d–f) marked crypt distortion with extensive crypt abscesses in the epithelium ((d) 200x, (e) 100x, and (f) 200x).</div>

Case Reports in Pathology

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Figure 3: Newly Diagnosed Colonic Adenocarcinoma: The Presenting Sign in a Young Woman with Undiagnosed Crohn’s Disease in the Absence of Primary Sclerosing Cholangitis and a Normal Microsatellite Instability Profile 

Figure 3 | Newly Diagnosed Colonic Adenocarcinoma: The Presenting Sign in a Young Woman with Undiagnosed Crohn’s Disease in the Absence of Primary Sclerosing Cholangitis and a Normal Microsatellite Instability Profile 