PAX8 Distinguishes Diffuse Large B-Cell Lymphoma Mimicking Sarcoma

Figure 3

Reevaluation of the original dura/calvarium lesion is consistent with diffuse large B-cell lymphoma. (a-b) Immunostains for LCA and PAX8 were diffusely and strongly immunoreactive in the tumor, supporting the diagnosis of lymphoma. The presence of CD20 and the absence of CD3 in neoplastic cells were consistent with a lymphoma of B-cell lineage (CD3 is present in nonneoplastic T-cell lymphocytes).

(a) LCA

(b) PAX8

(c) CD20

(d) CD3