Uterine Carcinosarcoma with Alpha-Fetoprotein-Producing Hepatoid Component: A Case Report and Literature Review

Table 1

Previously reported cases of uterine carcinosarcoma with hepatoid adenocarcinoma component.

	Case 1 (Takano et al.)	Case 2 (Kawaguchi et al.)	Case 3 (Kawaguchi et al.)
Age	63	63	82
Components	Endometrioid adenocarcinoma; Hepatoid adenocarcinoma; Spindle cell sarcoma	Hepatoid adenocarcinoma; Rhabdomyosarcoma	Endometrioid adenocarcinoma; Hepatoid adenocarcinoma; Spindle cell sarcoma
IHC	AFP +	AFP +	AFP +
Pre-op AFP	5060 ng/ml	10,131 ng/ml	401 ng/ml
Post-op AFP	< 10 ng/ml	< 20 ng/ml	< 20 ng/ml
Adjuvant	Paclitaxel + carboplatin	Paclitaxel + carboplatin	None
Outcome	Disease free at 12 months	Disease free at 24 months	Serum AFP rise; Died of lung recurrence at 12 months