An Inguinal Perivascular Epithelioid Cell Tumor Metastatic to the Orbit

Figure 3

Histology and immunochemistry of malignant PEComa. (a) Malignant cells in a concentric arrangement around blood vessels (H&E, 100x). (b) Epithelioid cells with granular light eosinophilic cytoplasm and oval nuclei with small nucleoli (H&E, 400x). (c) Melan-A demonstrates salient cytoplasmic immunoreactivity, supporting melanocytic phenotype (Melan-A (MART-1), 400x). (d) HMB-45 demonstrates salient cytoplasmic immunoreactivity, supporting melanocytic phenotype (HMB-45, 400x).

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