Primary Chordoma of the Nasopharynx: A Rare Case Report and Review of the Literatures

Table 1

No	References	Age/Sex	Chief complaint	Radiology	Bony involvement	Differential diagnosis	Tumor size (cm)	Gross	Pathology
1	Handosa Bey, 1949 [13]	16/F	Nasal obstruction for 2.5 years, headache	Mass in the skull base (sphenoid-base), filling nasophryngeal cavity	Bony trabecula involvement	Osteoclastoma	N/A	Soft friable tissue	Classic type
2	Seltzer et al., 1961 [14]	24/F	Six months of difficulty in swallowing, strangling sensation, moderate pain localized in the back of the throat, nasal speech	Large lobular and tender mass over the left nasopharyngeal floor	No erotion, nor other involvement of bone	Retropharyngeal abcess, infected cyst of the pharynx	4 × 4	Lobulated, soft, whitish mass with a cleft in the center	Classic type
3	Hingorani et al., 1970 [15]	62/M	Three months of progresive left-sided nasal obstruction	Large nasopharyngeal mass sitting on the sphenoidal sinus	Some bony spiculation and erosion	Chondrosarcoma cannot be positively excluded	N/A	Lobulated, fleshy, friable, brownish grey	Chondroid type
4	Maru et al., 1988 [16]	52/M	Nine months of nasal obstruction, bilateral hearing impairment	A huge soft tissue mass completely occupying the nasoppharyrtx and protruding into the orophaxynx	No bone involvement	Chondroma, Chondrosarcoma	8 × 6	A globular smooth mass	Classic type
5	Maru et al., 1988 [16]	20/M	Painful swelling of the right side of the face for 4 months	Soft-tissue mass in the right maxillary antrum with bone destruction of the medial, and anterolateral walls and roof	Involving anterolateral wall ofthe right maxilla, alveolar margin, gingivo-buccal sulcus and hard palate	chondrosarcoma	N/A	Soft-tissue mass with bone destruction	Classic type
6	Boyle et al., 1954 [17]	43/M	Double vision for 12 months, nasal obstruction for 3 months, and severe periotbital headaches and deafness	Mass instilled into the nose until sphenoid sinus	Bone destruction at the base of the skull	Nasopharyngeal carcinoma, adenocarcinoma	N/A	Hard and smooth lobulated tumour in a mucinous substance	Classic type
7	Hampal et al., 1992 [18]	80/F	Six months of dysphagia for solids and weight loss	Well circumscribed mass in the left parapharyngeal space	Absence of bony/spine involvement	Nasopharyngeal carcinoma	4 × 4	Greyish-white with a lobulated surface and gelatinous on the cut surface	Classic type
8	Wright et al., 1967 [19]	16/M	Complete bilateral nasal obstruction and nose bleeds for several months	Soft tissue swelling filling the nasopharynx	No bone involvement	Nasopharyngeal carcinoma	8 × 2	Swelling mass	Classic type
9	Wright et al., 1967 [19]	26/F	Increasing bilateral nasal obstruction	Large soft tissue mass filling the nasopharynx	No bone involvement	Nasopharyngeal carcinoma	N/A	Large tumor mass	Classic type
10	Wright et al., 1967 [19]	53/F	Right-sided headaches for 8 months, diplopia, numbness of the right cheek, tongue and gums, tinnitus, and deafness on the right side	Mass in the nasopharynx with erosion part of the right middle cranial fossa and pituitary fossa	Extension of erosion into the left middle cranial fossa and petrous apex	Nasopharyngeal carcinoma	N/A	Large tumor mass	Classic type
11	Wright et al., 1967 [19]	52/M	Left frontal pain and a drooping upper eyelid	Raised intracranial pressure with erosion of the pituitary fossa and destruction of the sphenoid and adjacent left ethmoid cells	Destruction of sphenoid, ethmoid and pituitary fossa	Nasopharyngeal carcinoma	N/A	Firm blue cyctic swelling	Classic type
12	Nguyen et al., 2009 [3]	8/F	Nasal obstruction, dryness of the mouth, difficulty in breathing,	Midline lobular and expansile mass with internal septation centered in the nasopharynx	Bony lytic changes along the anterior surface of the clivus (5/5)	Nasopharyngeal carcinoma, NonHodgkin lymphoma	N/A	Lobulated	Classic type
13	Nguyen et al., 2009 [3]	65/F
14	Nguyen et al., 2009 [3]	56/M
15	Nguyen et al., 2009 [3]	53/M
16	Nguyen et al., 2009 [3]	32/F
17	Yan et al., 2010 [1]	13/M	One to five years of nasal obstruction, headache and hearing loss (2/4)	Lobular and expansile nasopharyngeal mass with irregular intra tumor calsification	No bony involvement into the clivus	Nasopharyngeal Carcinoma, Juvenile Nasopharyngeal Angiofibroma	2.5–8.2	Lobulated, well defined with intra tumor septa	Classic type
18	Yan et al., 2010 [1]	31/M
19	Yan et al., 2010 [1]	38/M
20	Yan et al., 2010 [1]	66/F
21	Present case	26/M	Three years of nasal obstruction and congestion	Lobulated naso-oropharyngeal mass with displacement of uvula anteriorly	No bony involvement into the clivus	Naso-oropharyngeal cystic mass/abcess.	5 × 6	Lobulated, brownish white, some parts with black spot	Classic type

N/A = Not Available