Bone Marrow Burkitt Lymphoma in a Child
Photographs of bone marrow biopsy with primary Burkitt lymphoma. Low magnification showed a (a) hypercellular bone marrow with (b) monotonous infiltration of medium-sized lymphocytes that displayed (c) many mitotic (arrowhead) and apoptotic figures (arrow). Immunohistochemical analysis of lymphoma cells showed positivity for (d) CD20, (e) CD10, (f) Bcl-6, and (g) c-myc, while (h) Bcl-2 was negative. (i) Ki67 proliferative rate of tumor cells was nearly 100%.