Involvement of Annexin A2 Expression and Apoptosis in Reverse Polarization of Invasive Micropapillary Carcinoma of the Breast

Figure 4

Multiple apoptosis in the right breast cancer I. (a) Concentrated vacuoles are partially or circumferentially found at the periphery of each component in the background tumor (arrowheads). H&E stain, scale bar: 50 μm. (b) Apoptotic bodies and cells are scattered in the peripheral vacuoles (arrowheads), and inflammatory cell infiltration is inconspicuous. H&E stain, scale bar: 50 μm. (c) Positive reactions are widespread mainly at the periphery of the background tumor components. M30 CytoDEATH immunostain, scale bar: 100 μm. (d) Image corresponding to (b). Apoptotic bodies and cells represent immunoreactivity (arrowheads), and the positivity is also observed at the rim of the peripheral vacuoles (arrows). M30 CytoDEATH immunostain, scale bar: 50 μm.

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