Case Report
A Review Leveraging a Rare and Unusual Case of Basal Cell Carcinoma of the Prostate
Table 2
A summary of prostatic BCC studies (empty cells: no information was available).
| Year | Study | Sample size | Morphology | IHC | FISH | ACC-like pattern | Desmo-plasia | PNI | CK7 (+) | CK20 (+) | HMWCK (+) | p63 (+) | Race-mase (+) | NKX3.1 (+) | PSA (+) | PSAP (+) | Bcl-2 (+) | Ki-67 >20% | MYB rearrangement | MYB-NFIB fusion |
| Case series with>1 case report | | | | | | | | | | | | | | | | 1975 | Tannerbaum [12] | 2 | 100% | | | | | | | | | | | | | | | 1984 | Reed [11] | 4 | 100% | | | | | | | | | | | | | | | 1988 | Young [13] | 2 | 100% | | | | | | | | | 50% | 50% | | | | | 1988 | Grignon [7] | 2 | 100% | | 50% | | | 100% | | | | 0% | 0% | | | | | 1993 | Devaraj [6] | 4 | 100% | | 25% | | | 100% | | | | 50% | 50% | | | | | 2003 | Iczkowski [8] | 19 | 63% | | 26% | 100% | 0% | 100% | 86% | 0% | | 20% | 13% | | | | | 2004 | McKenny [10] | 4 | 75% | 0% | 100% | | | 75% | 75% | | | 0% | | | | | | 2007 | Ali [3] | 29 | 64% | 71% | 14% | | | | 100% | 27% | | | | 92% | 57% | | | 2013 | Chang [5] | 3 | 0% | | | | | 100% | 100% | | | | | 100% | 100% | | | 2015 | Bishop [4] | 12 | 58% | | | | | | | | | | | | | 17% | | 2019 | Magers [9] | 30 | 64% | 14% | 64% | | | | | | | | | | | | 47% | Single case report | | | | | | | | | | | | | | | | | 1974 | Frankel [2] | 1 | + | | | | | | | | | | | | | | | 1978 | Kramer [35] | 1 | + | | + | | | | | | | | | | | | | 1984 | Kuhajda [36] | 1 | + | | – | | | | | | | – | – | | | | | 1984 | Chan [29] | 1 | + | | – | | | | | | | | | | | | | 1986 | Gilmour [31] | 1 | + | | | | | | | | | | | | | | | 1991 | Ahn [27] | 1 | + | | + | | | | | | | | | | | | | 1992 | Denholm [21] | 1 | – | – | – | | | + | | | | – | – | | | | | 1993 | Cohen [20] | 1 | + | | | | | | | | | – | – | | | | | 1996 | Hasan [32] | 1 | – | | | | | | | | | | | | | | | 2001 | Minei [38] | 1 | + | | | | | | | | | – | – | | | | | 2002 | Schmid [41] | 1 | + | | + | | | | | | | | | | | | | 2003 | Mastropasqua [37] | 1 | – | | + | – | – | + | + | | | – | – | | | | | 2004 | Parada [39] | 1 | – | + | | | | + | | | | – | – | | | | | 2004 | Tulunay [45] | 1 | + | | | | | + | | | | – | – | | | | | 2006 | Fayyad [30] | 1 | + | | | + | – | + | | | | – | | Weak+ | | | | 2008 | Hudson [33] | 1 | + | | | | | + | + | | | – | | + | + | | | 2008 | Segawa [42] | 1 | – | | | – | – | + | + | | | – | Weak+ | | | | | 2010 | Bohn [28] | 1 | + | | + | + | – | + | + | | | – | – | Focal+ | 20% | | | 2010 | Komura [34] | 1 | – | | | + | – | + | + | | | – | Weak+ | | | | | 2012 | Stearns [43] | 1 | – | | | | | | | | | | | | | | | 2013 | Rodriguez-Carlin [40] | 1 | + | | + | | | + | + | | | | | + | | | | 2014 | Tsuruta [44] | 1 | – | | | | + | + | + | | | | | + | 10% | | | 2019 | Shibuya [17] | 1 | – | | | | | | + | | | | – | | | | | Current case report | 1 | + | + | + | + | – | + | + | – | – | | | + | 30% | – | – |
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Some of these case series may have overlapped cases. |