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Case Reports in Pediatrics
Volume 2013, Article ID 218124, 4 pages
Case Report

Anatomical Asplenia in Cat Eye Syndrome: An Expansion of the Disease Spectrum

1Department of Pediatrics and Adolescent Medicine, Einstein Medical Center, Philadelphia, PA 19141, USA
2Clinical Genetics, Einstein Medical Center, Philadelphia, PA 19141, USA

Received 21 February 2013; Accepted 14 March 2013

Academic Editors: P. Pavone and M. Raes

Copyright © 2013 DeepakBabu Chellapandian and Adele Schneider. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We report a patient with Cat eye syndrome (CES) associated with anatomical asplenia. To the best of our knowledge, there have been no prior reports of this association. Screening for asplenia in CES is potentially important, as asplenia places patients at increased risk for life-threatening bacterial infections. Hence patients with CES without a spleen may require the same routine precautions as any other asplenic patients, with penicillin prophylaxis and immunizations to protect against encapsulated organisms such as Streptococcus pneumoniae, Haemophilus influenzae type b, and Neisseria meningitidis.