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Case Reports in Pediatrics
Volume 2013 (2013), Article ID 931703, 3 pages
http://dx.doi.org/10.1155/2013/931703
Case Report

Concurrent Adrenal Neuroblastoma and Kawasaki Disease: A Report of a Rare Case

1Pediatric Congenital Hematologic Disorders Research Center, Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2Department of Pediatric Infectious Diseases, Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3Department of Pediatric Pathology, Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4Department of Internal Medicine, Eastern Virginia Medical School, Norfolk, VA, USA

Received 15 December 2012; Accepted 13 January 2013

Academic Editors: P. Czauderna and A. Gedalia

Copyright © 2013 Samin Alavi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Kawasaki disease (KD) is a systemic vasculitis of unknown etiology and a leading cause of acquired heart disease. It is assumed that there is an activation of the immune system by an infectious trigger in a genetically susceptible host. Neuroblastoma is the most common extracranial solid tumor in young children. It mainly originates from primordial neural crest cells that generate the adrenal medulla and sympathetic ganglia. A diagnosis of concurrent KD and neuroblastoma in a living child has been made in only one previous report. We report the second case and review the literature.