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Case Reports in Pediatrics
Volume 2015, Article ID 738571, 4 pages
http://dx.doi.org/10.1155/2015/738571
Case Report

Short Stature in Chronic Kidney Disease Treated with Growth Hormone and an Aromatase Inhibitor

1Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD 21201, USA
2Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
3Department of Pediatrics, University of Iowa Children’s Hospital, Iowa City, IA 52242, USA
4Department of Pediatrics, Sinai Hospital, Baltimore, MD 21215, USA

Received 2 March 2015; Accepted 14 May 2015

Academic Editor: Ashraf T. Soliman

Copyright © 2015 Susan R. Mendley et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We describe an alternative strategy for management of severe growth failure in a 14-year-old child who presented with advanced chronic kidney disease close to puberty. The patient was initially treated with growth hormone for a year until kidney transplantation, followed immediately by a year-long course of an aromatase inhibitor, anastrozole, to prevent epiphyseal fusion and prolong the period of linear growth. Outcome was excellent, with successful transplant and anticipated complete correction of height deficit. This strategy may be appropriate for children with chronic kidney disease and short stature who are in puberty.