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Case Reports in Pediatrics
Volume 2016, Article ID 5437971, 3 pages
Case Report

A Physician’s Nightmare: Fever of Unknown Origin

1Upstate Medical University, Syracuse, NY 13210, USA
2Auburn Community Hospital, Auburn, NY 13021, USA
3Division of Pediatric Gastroenterology, Hepatology & Nutrition, Upstate Medical University, Golisano Children’s Hospital, Syracuse, NY 13210, USA

Received 15 April 2016; Accepted 13 June 2016

Academic Editor: Daniel K. L. Cheuk

Copyright © 2016 Sana Din et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Fever of unknown origin (FUO) remains to be a challenge despite advancement in diagnostic technologies and procedures. FUO is considered when fever presents intermittently without an explanation. It has been linked to various etiologies, which makes it difficult to diagnose. We present the case of 18-month-old female with recurrent fever, splenomegaly, abdominal pain, and constipation. The workup for her symptoms revealed wandering spleen. Wandering spleen is a result from excessive laxity or absence of splenic ligaments. The patient underwent splenectomy and was advised to continue on Senna, Miralax, and high fiber diet. Her mother reported that the fever is no longer present and there is marked improvement in her constipation and abdominal pain after splenectomy.