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Case Reports in Pediatrics
Volume 2016, Article ID 7070125, 2 pages
Case Report

Airway Management in a Patient with Wolf-Hirschhorn Syndrome

Department of Anesthesiology, Duke University Medical Center, DUMC 3094, Durham, NC 27710, USA

Received 30 July 2016; Accepted 6 September 2016

Academic Editor: Pietro Strisciuglio

Copyright © 2016 John F. Gamble et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We present a case of a 3-month-old female with Wolf-Hirschhorn syndrome (WHS) undergoing general anesthesia for laparoscopic gastrostomy tube placement with a focus on airway management. WHS is a rare 4p microdeletion syndrome resulting in multiple congenital abnormalities, including craniofacial deformities. Microcephaly, micrognathia, and glossoptosis are common features in WHS patients and risk factors for a pediatric airway that is potentially difficult to intubate. We discuss anesthesia strategies for airway preparation and management in a WHS patient requiring general anesthesia with endotracheal intubation.