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Case Reports in Pediatrics
Volume 2017, Article ID 1329489, 4 pages
Case Report

Immune Thrombocytopenia in a Child with Neuroblastoma

1Department of Pediatrics, Acibadem University Medical Faculty, Istanbul, Turkey
2Department of Pediatrics, Acibadem Maslak Hospital, Istanbul, Turkey
3Department of Pathology, Acibadem Maslak Hospital, Istanbul, Turkey
4Department of Pediatric Surgery, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey

Correspondence should be addressed to Hasan Tarkan Ikizoglu; moc.liamg@inakrath

Received 2 May 2017; Revised 1 July 2017; Accepted 13 August 2017; Published 14 September 2017

Academic Editor: Edvige Veneselli

Copyright © 2017 Hasan Tarkan Ikizoglu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Thrombocytopenia is a frequent finding in patients with solid tumors. It is usually caused by bone marrow infiltration or by myelosuppression due to anticancer therapy; however immune thrombocytopenia (ITP) associated with solid tumors is rare. Neuroblastoma is the most common extracranial solid tumor in children. Here we report the case of a two-year-nine-month-old patient with adrenal neuroblastoma who presented with ITP. Paraneoplastic ITP was considered in the differential diagnosis. Bone marrow infiltration and other causes of thrombocytopenia were excluded and the patient was treated with intravenous immunoglobulin and tumor resection. Platelet count increased rapidly after surgery and complete remission of ITP was achieved.