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Case Reports in Pediatrics
Volume 2017, Article ID 6073619, 3 pages
https://doi.org/10.1155/2017/6073619
Case Report

Split-Hand Malformation in a 4-Year-Old Child

1Department of Pharmacology, Postgraduate Institute of Medical Education and Research and Dr. Ram Manohar Lohia Hospital, New Delhi, India
2Department of Pediatrics, Richmond University Medical Centre, Staten Island, NY, USA
3Department of Radiology, University of Texas Health Science Centre, San Antonio, TX, USA

Correspondence should be addressed to Girish Gulab Meshram; ni.oc.oohay@32hsirigrd

Received 27 April 2017; Revised 15 June 2017; Accepted 5 July 2017; Published 3 August 2017

Academic Editor: Maria Moschovi

Copyright © 2017 Girish Gulab Meshram et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. T. van Silfhout, P. C. van den Akker, T. Dijkhuizen et al., “Split hand/foot malformation due to chromosome 7q aberrations(SHFM1): Additional support for functional haploinsufficiency as the causative mechanism,” European Journal of Human Genetics, vol. 17, no. 11, pp. 1432–1438, 2009. View at Publisher · View at Google Scholar · View at Scopus
  2. A. Jamsheer, “Genetic background of isolated forms of congenital malformations of the hand,” Medycyna Wieku Rozwojowego, vol. 12, no. 3, pp. 729–737, 2008. View at Google Scholar · View at Scopus
  3. A. Sowińska-Seidler, M. Socha, and A. Jamsheer, “Split-hand/foot malformation - molecular cause and implications in genetic counseling,” Journal of Applied Genetics, vol. 55, no. 1, pp. 105–115, 2014. View at Publisher · View at Google Scholar · View at Scopus
  4. F. Gurrieri and D. B. Everman, “Clinical, genetic, and molecular aspects of split-hand/foot malformation: An update,” American Journal of Medical Genetics, Part A, vol. 161, no. 11, pp. 2860–2872, 2013. View at Publisher · View at Google Scholar · View at Scopus
  5. M. J. Blitz and B. Rochelson, “Prenatal diagnosis of ectrodactyly in the first trimester by three-dimensional ultrasonography,” American Journal of Perinatology Reports, vol. 06, no. 01, pp. e142–e144, 2016. View at Publisher · View at Google Scholar
  6. D. Conte, G. Garaffo, N. L. Iacono et al., “The apical ectodermal ridge of the mouse model of ectrodactyly Dlx5;Dlx6-/- shows altered stratification and cell polarity, which are restored by exogenous Wnt5a ligand,” Human Molecular Genetics, vol. 25, no. 4, pp. 740–754, 2016. View at Publisher · View at Google Scholar
  7. M. B. Rasmussen, S. Kreiborg, P. Jensen et al., “Phenotypic subregions within the split-hand/foot malformation 1 locus,” Human Genetics, vol. 135, no. 3, pp. 345–357, 2016. View at Publisher · View at Google Scholar · View at Scopus
  8. P. R. Manske and M. N. Halikis, “Surgical classification of central deficiency according to the thumb web,” Journal of Hand Surgery, vol. 20, no. 4, pp. 687–697, 1995. View at Publisher · View at Google Scholar · View at Scopus
  9. A. Blattner, A. R. Huber, and B. Röthlisberger, “Homozygous nonsense mutation in WNT10B and sporadic Split-Hand/Foot Malformation (SHFM) with autosomal recessive inheritance,” American Journal of Medical Genetics, Part A, vol. 152, no. 8, pp. 2053–2056, 2010. View at Publisher · View at Google Scholar · View at Scopus