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Case Reports in Pediatrics
Volume 2017, Article ID 7940365, 5 pages
https://doi.org/10.1155/2017/7940365
Case Report

Cryptogenic Cirrhosis and Hepatopulmonary Syndrome in a Boy with Hepatic Hemangioma in Botswana: A Case Report and Review of the Literature

1Department of Paediatrics and Adolescent Health, Faculty of Medicine, University of Botswana, Gaborone, Botswana
2Baylor College of Medicine, Texas Children’s Cancer and Hematology Centers, Houston, TX, USA
3Paediatric Liver Transplant Unit, Wits University Donald Gordon Medical Centre, Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South Africa
4Department of Paediatric Surgery, School of Clinical Medicine, University of Witwatersrand, Johannesburg, South Africa
5Wits University Donald Gordon Medical Centre, Drs Gritzman & Thatcher Inc., Johannesburg, South Africa
6Department of Paediatrics, Steve Biko Academic Hospital, University of Pretoria, Pretoria, South Africa

Correspondence should be addressed to Francis Msume Banda; ku.oc.oohay@adnabmf

Received 24 June 2017; Revised 9 October 2017; Accepted 31 October 2017; Published 19 December 2017

Academic Editor: Roland Broadbent

Copyright © 2017 Francis Msume Banda et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Ministry of Health, “Republic of Botswana: handbook of the Botswana 2016 integrated HIV clinical care guidelines,” February 2017, http://www.moh.gov.bw/Publications/Handbook_HIV_treatment_guidelines.pdf. View at Google Scholar
  2. N. Bajenaru, V. Balaban, F. Săvulescu, I. Campeanu, and T. Patrascu, “Hepatic hemangioma—review,” Journal of Medicine and Life, vol. 8, pp. 4–11, 2015. View at Google Scholar
  3. Y. Nakanuma, “Review: non-neoplastic nodular lesions in the liver,” Pathology International, vol. 45, no. 10, pp. 703–714, 1995. View at Publisher · View at Google Scholar
  4. A. Akhavan and J. H. Zippin, “Current treatments for infantile hemangiomas,” Journal of Drugs in Dermatology, vol. 9, no. 2, pp. 176–180, 2010. View at Google Scholar
  5. H. Zaher, H. Rasheed, R. A. Hegazy, R. A. Hegazy, D. M. Abdelhalim, and H. I. Gawdat, “Oral propranolol: an effective, safe treatment for infantile hemangiomas,” European Journal of Dermatology, vol. 21, no. 4, pp. 558–563, 2011. View at Publisher · View at Google Scholar · View at Scopus
  6. J. Bertrand, R. Sammour, and C. McCuaig, “Propranolol in the treatment of problematic infantile hemangioma: review of 35 consecutive patients from a vascular anomalies clinic,” Journal of Cutaneous Medicine and Surgery, vol. 16, no. 5, pp. 317–323, 2012. View at Publisher · View at Google Scholar
  7. V. Ho, “Current concepts in the management of hepatopulmonary syndrome,” Vascular Health and Risk Management, vol. 4, no. 5, pp. 1035–1041, 2008. View at Publisher · View at Google Scholar
  8. R. Rodriguez-Roisin and M. J. Krowka, “Hepatopulmonary syndrome—a liver-induced lung vascular disorder,” New England Journal of Medicine, vol. 358, no. 22, pp. 2378–2387, 2008. View at Publisher · View at Google Scholar · View at Scopus
  9. M. J. Stewart, “Contrast echocardiography,” Heart, vol. 89, no. 3, pp. 342–348, 2003. View at Publisher · View at Google Scholar
  10. J. Offer, L. Green, A. R. Houghton, and J. Campbell, “A case of hepatopulmonary syndrome,” Echo Research and Practice, vol. 2, no. 2, pp. K25–K27, 2015. View at Publisher · View at Google Scholar
  11. A. H. M. Alizade, S. R. Fatemi, V. Mirzaee et al., “Clinical features of hepatopulmonary syndrome in cirrhotic patients,” World Journal of Gastroenterology, vol. 12, no. 12, pp. 1954–1956, 2006. View at Publisher · View at Google Scholar
  12. A. O. Silverio, D. C. Guimaraes, L. F. Elias, E. O. Milanez, and S. Naves, “Are the spider angiomas skin markers of hepatopulmonary syndrome?” Arquivos de Gastroenterologia, vol. 50, no. 3, pp. 175–179, 2013. View at Publisher · View at Google Scholar · View at Scopus
  13. G. Cremora, T. W. Higenbottam, V. Mayoral et al., “Elevated exhaled nitric oxide in patients with hepatopulmonary syndrome,” European Respiratory Journal, vol. 8, no. 8, pp. 1883–1885, 1995. View at Google Scholar
  14. M. R. Arguedas, B. B. Drake, A. Kapoor, and B. Fallon, “Carboxyhemoglobin levels in cirrhotic patients with and without hepatopulmonary syndrome,” Gastroenterology, vol. 128, no. 2, pp. 328–333, 2005. View at Publisher · View at Google Scholar · View at Scopus
  15. P. Berthelot, J. G. Walker, S. Sherlocks, and L. Reid, “Arterial changes in the lungs in cirrhosis of the liver-lung spider nevi,” New England Journal of Medicine, vol. 274, no. 6, pp. 291–298, 1966. View at Publisher · View at Google Scholar
  16. M. J. Krowka, G. A. Wiseman, O. L. Burnett et al., “Hepatopulmonary syndrome: a prospective study of relationships between severity of liver disease, PaO2 response to 100% oxygen and brain uptake after (99m) Tc MAA lung scanning,” Chest, vol. 118, no. 3, pp. 615–624, 2000. View at Google Scholar
  17. R. B. Pinto, A. C. R. Schneider, and T. R. Da Silveira, “Cirrhosis in children and adolescents: an overview,” World Journal of Hepatology, vol. 7, no. 3, pp. 392–405, 2015. View at Publisher · View at Google Scholar · View at Scopus
  18. A. Slogrove, B. Reikie, S. Naidoo et al., “HIV-exposed uninfected infants are at increased risk for severe infections in the first year of life,” Journal of Tropical Pediatrics, vol. 58, no. 6, pp. 505–508, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. R. Rodriguez-Roisin and M. J. Krowka, “Is severe arterial hypoxaemia due to hepatic disease an indication for liver transplantation? A new therapeutic approach,” European Respiratory Journal, vol. 7, no. 5, pp. 839–842, 1994. View at Google Scholar
  20. L. S. Eriksson, C. Soderman, B. G. Ericzon, L. Eleborg, J. Wahren, and G. Hedenstierna, “Normalization of ventilation perfusion relationships after liver transplantation in decompensated cirrhosis: evidence for a hepatopulmonary syndrome,” Hepatology, vol. 12, no. 6, pp. 1350–1357, 1990. View at Publisher · View at Google Scholar · View at Scopus
  21. J. J. McCloskey, C. Schleien, K. Schwarz, A. Klein, and P. Colombani, “Severe hypoxemia and intrapulmonary shunting reversed by liver transplantation in a pediatric patient,” Journal of Pediatrics, vol. 118, no. 6, pp. 902–904, 1991. View at Publisher · View at Google Scholar · View at Scopus
  22. J. M. LaBerge, M. L. Brandt, P. Lebecque et al., “Reversal of cirrhosis-related pulmonary shunting in two children by orthotopic liver transplantation,” Transplantation, vol. 53, no. 5, pp. 1135–1138, 1992. View at Google Scholar
  23. M. J. Krowka, R. H. Wiesner, and J. K. Heimbach, “Pulmonary contraindications, indications and MELD exceptions for liver transplantation: a contemporary view and look forward,” Journal of Hepatology, vol. 59, no. 2, pp. 367–374, 2013. View at Publisher · View at Google Scholar · View at Scopus
  24. M. J. Krowka, “Hepatopulmonary syndrome: what are we learning from interventional radiology, liver transplantation, and other disorders?” Gastroenterology, vol. 109, no. 3, pp. 1009–1013, 1995. View at Publisher · View at Google Scholar · View at Scopus
  25. K. L. Swanson, R. H. Wiesner, and M. J. Krowka, “Natural history of hepatopulmonary syndrome: impact of liver transplantation,” Hepatology, vol. 41, no. 5, pp. 1122–1129, 2005. View at Publisher · View at Google Scholar · View at Scopus
  26. M. R. Arguedas, G. A. Abrams, M. J. Krowka, and M. P. Fallon, “Postoperative evaluation outcomes and predictors of mortality in patients with hepatopulmonary syndrome undergoing liver transplantation,” Hepatology, vol. 37, no. 1, pp. 192–197, 2003. View at Publisher · View at Google Scholar · View at Scopus
  27. B. Song, M. Schulze, I. Goldschmidt, R. Haux, U. Baumann, and M. Marschollek, “Home monitoring and decision support for international liver transplant children,” Studies in Health Technology and Informatics, vol. 192, pp. 268–272, 2013. View at Google Scholar