Craniofacial and Dental Manifestations of Melnick–Needles Syndrome: Literature Review and Orthodontic Management

Table 1

Systematic review since 2000 (PubMed and Scopus): surgical procedures in patients with MNS.

Article	Publication type	No. of patients	Time of follow-up after surgery	Time of surgery	Surgery’s type	Observations
Lykissas et al. [8]	Case report	2	8 years (25 years old)	17 years	Spine surgery	Well-maintained correction and no evidence of implant breakage
			5 years (18 years old	18 years
Jung et al. [1]	Case report	1	8 months	18 years	Orthognatic surgery (BSSO)	Functional rehabilitation and aesthetic improvement have been achieved
Chen et al. [9]	Case report	1	No information	16 years	Orthognatic surgery (mandible)	Successful lengthening of mandible and full reconstruction of upper airway
Kelley et al. [10]	Case report	1	2 years (23 years old)	21 years	Orthognatic surgery (mandible)	The patient experienced complete resolution of symptoms and has been pain-free for more than 24 months
Molina et al. [11]	Case report	1	No information	No information	Orthognatic surgery	Occlusion had changed from a class II to a class III relationship. Snoring was eliminated. No need for tracheotomy in the future.