Case Reports in Pediatrics / 2019 / Article / Tab 2

Case Series

Neonatal Chylothoraces: A 10-Year Experience in a Tertiary Neonatal Referral Centre

Table 2

Case series of neonatal chylothorax.

Author and yearNumber of neonatesVentilation (days)Number given MCT feedsNumber treated with octreotide and doseOctreotide duration (days)Octreotide efficacyPleurodesis or thoracic duct ligation

Altuncu et al. (2007) [5]3N/Rn = 3n = 1 (1–10 mcg/kg/hr)28No responsen = 1
Matsukuma et al. (2009) [6]2N/Rn = 2n = 2 (0.5–10 mcg/kg/hr)16–20No responsen = 2
Bellini et al. (2012) [7]3030n = 28n = 6 (1–10 mcg/kg/hr)8–38Decreased chylous production, but not quantifiedn = 1
Horvers et al. (2012) [8]716n = 7n = 7 (2–12 mcg/kg/hr)Median 22 (11–46)Possible response in two neonatesn = 0
Shah and Sinn (2012) [9]630n = 6n = 6 (0.5–10 mcg/kg/hr)Median 20 (4–41)Resolution in five neonatesn = 0
Downie et al. (2013) [1]108n = 7n = 3 (3.5–10 mcg/kg/hr)N/RResponse in two neonates: not quantifiedn = 0
Landis et al. (2013) [10]1111N/Rn = 6 (1–13 mcg/kg/hr)N/RNo responsen = 0
Bialkowski et al. (2015) [2]2823n = 25n = 7 (3–10 mcg/kg/hr)Median 21 (10–45)No responsen = 0
Hua et al. (2016) [11]41N/Rn = 3 (N/A)14No responsen = 4
Yin et al. (2017) [12]1413n = 12n = 3 (1–6 mcg/kg/hr)Median 6Average drain output significantly lower: three days after treatment. Median 62 ml versus 133 ml ()n = 0
Shillitoe et al. (2018) [13]21N/Rn = 2n = 1 (maximum dose 10 mcg/kg/hr)N/ROn the maximum dose there was a 50% reduction in five daysn = 0
Zaki et al. (2018) [14]9N/Rn = 9n = 9 (1–10 mcg/kg/hr)5–66Resolution in three neonates: not quantifiedn = 0

N/R: not reported.

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