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| Condition | Characteristics |
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| Jacquet erosive diaper dermatitis | Well-demarcated papules and nodules with central umbilications and punched-out ulcers in the genital or perianal areas; occurrence is usually in older patients |
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| Pseudoverrucous papules and nodules | Erythematous or gray, erosive or verrucous papules, nodules, or plaques; histopathology shows reactive acanthosis and psoriasiform epidermal hyperplasia without significant dermal infiltrate |
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| Candidal diaper dermatitis | Beefy red, erythematous rash with a scalloped border and a sharply demarcated margin in the diaper area; satellite papules and pustules along the margin are pathognomonic |
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| Seborrheic dermatitis | Nonpruritic, salmon-colored or erythematous, sharply demarcated patches with yellow-white, greasy scales on the diaper area, face, and intertriginous areas; scaling and crusting of the scalp |
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| Atopic dermatitis | History of atopic disease; pruritic eruption (papules, papulovesicles, prominent scaling, excoriations, and lichenification); indistinct border; chronically relapsing |
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| Perianal streptococcal dermatitis | Sharply circumscribed, tender perianal erythema; may be associated with rectal discomfort, rectal itching, painful defecation, and blood-streaked stools lesions |
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| Plaque psoriasis | Well-demarcated, annular, erythematous, round or oval, pruritic plaques with loosely adherent silvery-white micaceous scales; positive Auspitz sign; pitting of the nail |
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| Bullous impetigo | Sharply demarcated bulla without surrounding erythema; rupture of the bulla reveals a moist erythematous base that dries to form a shiny lacquer-like appearance; a narrow rim of scale at the edge of the ruptured lesion is pathognomonic |
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| Juvenile xanthogranuloma | Asymptomatic, well-demarcated, dome-shaped, firm, rubbery, round-to-oval papule or nodule; a pink-to-red lesion with a yellow tinge initially; over time, the lesion acquires a yellow-brown or orange hue and will often flatten overtime |
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| Molluscum contagiosum | Discrete, smooth, firm, waxy, dome-shaped papules with characteristic central dell or umbilication |
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| Acrodermatitis enteropathica | Acral and periorificial dermatitis; diarrhea; alopecia |
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| Nodular scabies | Extremely pruritic, erythematous nodules that can persist even after treatment of scabies; pruritus is most intense at night |
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| Langerhans cell histiocytosis | Seborrheic dermatitis-like eruption; erythematous/reddish-brown crusted/scaly papules/maculopapules/plaques/patches; eczematous lesions; bone lesion; anemia; thrombocytopenia; lymphadenopathy; hepatosplenomegaly |
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| Maculopapular cutaneous mastocytosis | Pruritic, erythematous to reddish-brown macules/papules on the trunk and proximal extremities; positive Darier sign |
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