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Case Reports in Psychiatry
Volume 2013, Article ID 367594, 4 pages
http://dx.doi.org/10.1155/2013/367594
Case Report

Clonazepam as Agonist Substitution Treatment for Benzodiazepine Dependence: A Case Report

1Vincent P. Dole Dual Diagnosis Unit, Department of Neurosciences, Santa Chiara University Hospital, University of Pisa, Via Roma, 67, 56100 Pisa, Italy
2Association for the Application of Neuroscientific Knowledge to Social Aims (AU-CNS), Lucca, 55045 Pietrasanta, Italy
3G. De Lisio Institute of Behavioural Sciences, 56100 Pisa, Italy

Received 17 December 2012; Accepted 14 January 2013

Academic Editors: D. De Leo and M. Kluge

Copyright © 2013 Angelo Giovanni Icro Maremmani et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. H. Naqvi, S. Hussan, and F. Dossa, “Benzodiazepine: slow sand of addiction,” Journal of the Pakistan Medical Association, vol. 59, no. 6, pp. 415–417, 2009. View at Google Scholar · View at Scopus
  2. A. L. Lalive, U. Rudolph, C. Luscher, and K. R. Tan, “Is there a way to curb benzodiazepine addiction?” , Swiss Medical Weekly, vol. 141, Article ID w13277, 2011. View at Publisher · View at Google Scholar
  3. R. A. Sansone, K. A. Griffith, and L. A. Sansone, “Panic disorder, alcohol and substance abuse, and benzodiazepine prescription,” Primary Care Companion to the Journal of Clinical Psychiatry, vol. 7, no. 5, pp. 246–248, 2005. View at Google Scholar · View at Scopus
  4. M. F. Brunette, D. L. Noordsy, H. Xie, and R. E. Drake, “Benzodiazepine use and abuse among patients with severe mental illness and co-occurring substance use disorders,” Psychiatric Services, vol. 54, no. 10, pp. 1395–1401, 2003. View at Publisher · View at Google Scholar · View at Scopus
  5. A. Albiero, F. Brigo, M. Faccini et al., “Focal nonconvulsive seizures during detoxification for benzodiazepine abuse,” Epilepsy and Behaviour, vol. 23, no. 2, pp. 168–170, 2012. View at Publisher · View at Google Scholar
  6. D. S. Baldwin and B. Talat, “Should benzodiazepines still have a role in treating patients with anxiety disorders?” Human Psychopharmacology, vol. 27, no. 3, pp. 237–238, 2012. View at Publisher · View at Google Scholar
  7. S. Darke, J. Ross, K. Mills, M. Teesson, A. Williamson, and A. Havard, “Benzodiazepine use among heroin users: baseline use, current use and clinical outcome,” Drug and Alcohol Review, vol. 29, no. 3, pp. 250–255, 2010. View at Publisher · View at Google Scholar · View at Scopus
  8. M. Fatséas, C. Denis, E. Lavie, and M. Auriacombe, “Relationship between anxiety disorders and opiate dependence—a systematic review of the literature. Implications for diagnosis and treatment,” Journal of Substance Abuse Treatment, vol. 38, no. 3, pp. 220–230, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. M. M. Glatt, “Benzodiazepine abuse in alcoholics,” The Lancet, vol. 2, no. 8101, article 1205, 1978. View at Google Scholar · View at Scopus
  10. S. P. Kurtz, H. L. Surratt, M. A. Levi-Minzi, and A. Mooss, “Benzodiazepine dependence among multidrug users in the club scene,” , Drug and Alcohol Dependence, vol. 119, no. 1-2, pp. 99–105, 2011. View at Publisher · View at Google Scholar
  11. S. Dragt, D. H. Nieman, F. Schultze-Lutter et al., “Cannabis use and age at onset of symptoms in subjects at clinical high risk for psychosis,” Acta Psychiatrica Scandinavica, vol. 125, no. 1, pp. 45–53, 2012. View at Publisher · View at Google Scholar
  12. W. M. Compton and N. D. Volkow, “Abuse of prescription drugs and the risk of addiction,” Drug and Alcohol Dependence, vol. 83, supplement 1, pp. S4–S7, 2006. View at Publisher · View at Google Scholar · View at Scopus
  13. M. G. Farnsworth, “Benzodiazepine abuse and dependence: misconceptions and facts,” Journal of Family Practice, vol. 31, no. 4, pp. 393–400, 1990. View at Google Scholar · View at Scopus
  14. S. A. Stewart, “The effects of benzodiazepines on cognition,” Journal of Clinical Psychiatry, vol. 66, no. 2, pp. 9–13, 2005. View at Google Scholar · View at Scopus
  15. C. Salzman, “Benzodiazepine treatment of panic and agoraphobic symptoms: use, dependence, toxicity, abuse,” Journal of Psychiatric Research, vol. 27, no. 1, pp. 97–110, 1993. View at Publisher · View at Google Scholar · View at Scopus
  16. K. Rickels, E. Schweizer, W. G. Case, and D. J. Greenblatt, “Long-term therapeutic use of benzodiazepines. I. Effects of abrupt discontinuation,” Archives of General Psychiatry, vol. 47, no. 10, pp. 899–907, 1990. View at Google Scholar · View at Scopus
  17. M. Romach, U. Busto, G. Somer, H. L. Kaplan, and E. Sellers, “Clinical aspects of chronic use of alprazolam and lorazepam,” American Journal of Psychiatry, vol. 152, no. 8, pp. 1161–1167, 1995. View at Google Scholar · View at Scopus
  18. C. P. O'Brien, “Benzodiazepine use, abuse, and dependence,” Journal of Clinical Psychiatry, vol. 66, no. 2, pp. 28–33, 2005. View at Google Scholar · View at Scopus
  19. M. Liebrenz, L. Boesch, R. Stohler, and C. Caflisch, “Benzodiazepine dependence: when abstinence is not an option,” Addiction, vol. 105, no. 11, pp. 1877–1878, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. G. Poisnel, M. Dhilly, R. Le Boisselier, L. Barre, and D. Debruyne, “Comparison of five benzodiazepine-receptor agonists on buprenorphine-induced μ-opioid receptor regulation,” Journal of Pharmacological Sciences, vol. 110, no. 1, pp. 36–46, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. S. M. Juergens, “Benzodiazepines, other sedative, hypnotic, and anxiolytic drugs, and addiction,” in The Principles and Pratictice of Addictions in Psychiatry, N. S. Miller, Ed., pp. 177–178, WB Saunders, Philadelphia, Pa, USA, 1997. View at Google Scholar
  22. E. M. Sellers, D. A. Ciraulo, R. L. DuPont et al., “Alprazolam and benzodiazepine dependence,” Journal of Clinical Psychiatry, vol. 54, no. 10, pp. 64–75, 1993. View at Google Scholar · View at Scopus
  23. M. Liebrenz, L. Boesch, R. Stohler, and C. Caflisch, “Agonist substitution—a treatment alternative for high-dose benzodiazepine-dependent patients?” Addiction, vol. 105, no. 11, pp. 1870–1874, 2010. View at Publisher · View at Google Scholar · View at Scopus
  24. I. Maremmani, M. Pacini, S. Canoniero, J. Deltito, A. G. I. Maremmani, and A. Tagliamonte, “Dose determination in dual diagnosed heroin addicts during methadone treatment,” Heroin Addiction and Related Clinical Problems, vol. 12, no. 1, pp. 17–24, 2010. View at Google Scholar · View at Scopus
  25. V. P. Dole, M. E. Nyswander, and M. J. Kreek, “Narcotic blockade,” Archives of Internal Medicine, vol. 118, no. 4, pp. 304–309, 1966. View at Publisher · View at Google Scholar · View at Scopus
  26. I. Maremmani and M. Pacini, “The phases of treatment,” in The Principles and Practice of Methadone Treatment, I. Maremmani, Ed., pp. 87–96, Pacini Editore Medicina, Pisa, Italy, 2009. View at Google Scholar
  27. American Psychiatric Association, DSM-IV-TR. Diagnostic and Statistical Manual of Mental Disorders, American Psychiatric Association, Washington, DC, USA, 2000.
  28. G. Chouinard, “Issues in the clinical use of benzodiazepines: potency, withdrawal, and rebound,” Journal of Clinical Psychiatry, vol. 65, no. 5, pp. 7–12, 2004. View at Google Scholar · View at Scopus