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ECT | Medications | Energy/charge | Motor/EEG response | Clinical response |
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1 | Ziprasidone 60 mg twice daily, lamotrigine 200 mg before bed, and lorazepam 1 mg three times daily | 25% bifrontal 128.9 mc | 1 sec motor/36 sec EEG | Improved verbal response for 30 min and then back to catatonic state. Throughout the day, patient became more verbal and coherent and even expressed humor. |
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2 | Identical regimen as time point 1 | 40% bifrontal 204.2 mc | 10 sec motor/40 sec EEG | Less interactive, disoriented, with repetitive movements. |
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3 | Identical regimen as time point 1 | 50%/75% bifrontal1 258.7 mc | 1 sec motor/7 sec EEG 5 sec motor/48 sec EEG | Less energetic, increasingly drowsy, minimal interaction, decreased sleep, and pacing hallways. |
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4 | Ziprasidone 60 mg twice daily, lamotrigine 150 mg before bed, and lorazepam 0.5 mg three times daily | 75% bifrontal 377.4 mc | 33 sec motor/56 sec EEG | Very drowsy, psychomotor retardation, decreased sleep, waxy flexibility, and increased speech latency. |
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5 | Ziprasidone 80 mg twice daily, lamotrigine 150 mg before bed, and lorazepam 0.5 mg three times daily | 75% bifrontal 376.1 mc | 21 sec motor/29 sec EEG | Much more engaged, aware, conversational, and oriented to situation. |
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6 | Ziprasidone 80 mg twice a day, lamotrigine 150 mg before bed (held before ECT), and lorazepam 0.5 twice daily | 100% bifrontal 502.4 mc | 19 sec motor/34 sec EEG | Waxing/waning mutism, repetitive movements, and psychomotor retardation. |
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7 | Ziprasidone 80 mg twice daily, lamotrigine 150 mg before bed (held before ECT), and d/c lorazepam | 100% bifrontal 503.2 mc | 19 sec motor/34 sec EEG | Improved but still with low energy and very drowsy. |
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8 | Ziprasidone 40 mg am/80 mg pm, lamotrigine 150 mg before bed | 100% bitemporal 502.9 mc | 11 sec motor/56 sec EEG | Regaining energy, more engaged, with improved affect. |
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