Case Report

The Treatment of Clozapine-Withdrawal Delirium with Electroconvulsive Therapy

Table 1

Published case reports of syndromes precipitated by clozapine withdrawal treated with electroconvulsive therapy.

AuthorsPsychiatric diagnosisAgeSexClozapine daily dose (mg)Reason for clozapine discontinuationRebound syndromeResponse to ECT

Bastiampillai et al. [2]Bipolar Disorder51F15–500NonadherenceRecurrent maniaYes
Cerit et al. [8]Schizophrenia46M200NonadherenceCatatoniaNo
Koch et al. [10]Schizophrenia33F250LeukopaeniaCatatoniaPartial
Kumar et al. [11]Schizophrenia29M250Febrile neutropaeniaCatatoniaYes
Mendhekar et al. [12]Schizophrenia26M300NonadherenceNMS, psychosisYes
Bastiampillai et al. [13]Schizoaffective disorder58F150NonadherenceCatatonic, cholinergic, & serotonergic symptomsYes