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Case Reports in Psychiatry
Volume 2017, Article ID 2890436, 3 pages
https://doi.org/10.1155/2017/2890436
Case Report

Course of Neuropsychiatric Symptoms during Flares of Systemic Lupus Erythematosus (SLE)

University College London Hospitals NHS Trust, London, UK

Correspondence should be addressed to Gareth Garrett; ten.shn@tterraghterag

Received 14 December 2016; Accepted 7 February 2017; Published 23 February 2017

Academic Editor: Fabrice Jollant

Copyright © 2017 Gareth Garrett et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We present the case of a seventeen-year-old girl who presents with an interesting course of neuropsychiatric symptoms during several flares of SLE. The patient was diagnosed at the age of thirteen and has had four flares in total. The latter two flares included cutaneous and neuropsychiatric symptoms. The most recent flare occurred when she was aged seventeen. She had cutaneous symptoms which coincided with an episode of hypomania. Her mental state further deteriorated following steroid treatment. She exhibited affective and psychotic symptoms. Treatment with cyclophosphamide and olanzapine was associated with an improvement in both cutaneous and neuropsychiatric symptoms. Previously aged sixteen the patient had presented with cutaneous symptoms and a moderate depressive episode which was also exacerbated by steroid treatment. The patient’s mood improved when the dose of oral steroids was reduced to a daily dose of 15–20 mg prednisolone.