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Case Reports in Pulmonology
Volume 2013, Article ID 193830, 4 pages
Case Report

Mycobacterium interjectum Lung Infection

1Division of Pulmonary Medicine, Mayo Clinic Florida, 4500 San Pablo Road, Jacksonville, FL 32224, USA
2Division of Pulmonary Medicine and Infectious Disease, Mayo Clinic Florida, USA

Received 26 May 2013; Accepted 19 August 2013

Academic Editors: D. Franzen and C. Y. Tu

Copyright © 2013 M. C. Mirant-Borde et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A 62-year-old male presented with productive cough, weight loss, and night sweats. CXR revealed a right upper lobe cavitary lesion. Evaluation was negative for Mycobacterium tuberculosis, and sputum revealed Mycobacterium avium intracellulare (MAI). Since his clinical course was atypical for MAI, further investigations were pursued which identified Mycobacterium interjectum in lung specimens, a very rarely described etiology of pulmonary disease. Appropriate therapy with rifampin, intravenous amikacin, trimethoprim/sulfamethoxazole (TMP/SMX), and ethambutol resulted in clinical and radiographic improvement. This is the third case described over a period of 20 years of destructive lung disease in an immunocompetent adult due to M. interjectum.