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Case Reports in Pulmonology
Volume 2015 (2015), Article ID 283875, 4 pages
http://dx.doi.org/10.1155/2015/283875
Case Report

Metastatic Squamous Cell Carcinoma Component from an Adenosquamous Carcinoma of the Lung with Identical Epidermal Growth Factor Receptor Mutations

1Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH 43210, USA
2Department of Pathology, The Ohio State University College of Medicine, Columbus, OH 43210, USA
3Department of Radiology, The Ohio State University College of Medicine, Columbus, OH 43210, USA

Received 24 April 2015; Accepted 2 August 2015

Academic Editor: Nobuyuki Koyama

Copyright © 2015 Jarred Burkart et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. T. J. Lynch, D. W. Bell, R. Sordella et al., “Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib,” The New England Journal of Medicine, vol. 350, no. 21, pp. 2129–2139, 2004. View at Publisher · View at Google Scholar · View at Scopus
  2. S. M. Kang, H. J. Kang, J. H. Shin et al., “Identical epidermal growth factor receptor mutations in adenocarcinomatous and squamous cell carcinomatous components of adenosquamous carcinoma of the lung,” Cancer, vol. 109, no. 3, pp. 581–587, 2007. View at Publisher · View at Google Scholar · View at Scopus
  3. L. V. Sequist, B. A. Waltman, D. Dias-Santagata et al., “Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors,” Science Translational Medicine, vol. 3, no. 75, Article ID 75ra26, 2011. View at Publisher · View at Google Scholar
  4. S. P. D'Angelo, M. C. Pietanza, M. L. Johnson et al., “Incidence of EGFR exon 19 deletions and L858R in tumor specimens from men and cigarette smokers with lung adenocarcinomas,” Journal of Clinical Oncology, vol. 29, no. 15, pp. 2066–2070, 2011. View at Publisher · View at Google Scholar · View at Scopus